For many years Cricoid pressure (CP) has been a standard of care during induction crystal beaded candle holder of anaesthesia in emergency situations and where the patient is deemed at risk for aspiration of stomach contents (Rapid Sequence Induction or RSI).This review will examine the technique and its history; discuss the usual arguments present
Sarcopenia is defined by the age-related loss of skeletal muscle quality, which here relies on mitochondrial homeostasis.During aging, several mitochondrial features such as bioenergetics, dynamics, biogenesis, and selective autophagy (mitophagy) are altered and impinge on protein homeostasis, resulting in loss of muscle mass and function.Thus, mit
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The recent outbreak of pneumonia-causing COVID-19 in China is an urgent global public health issue with an increase in mortality here and morbidity.Here we report our modelled homo-trimer structure of COVID-19 spike glycoprotein in both closed (ligand-free) and open (ligand-bound) conformation, which is involved in host cell adhesion.We also predic